SAM has demonstrated impressive results in the treatment of osteoarthritis. SAM is required for the synthesis of
cartilage components and appears to exert pain-relieving and anti-inflammatory properties.14,15
At least 21,524 patients with osteoarthritis have participated in clinical trials using SAM supplementation. Even
when tested against commonly used anti-inflammatory drugs (i.e. Advil, Motrin, Nuprin, Naproxen) SAM
supplementation has provided significant relief of osteoarthritic symptoms and improved joint function and quality of
life. An MRI (magnetic resonance imaging) study demonstrated increased cartilage formation in 14 patients with
osteoarthritis of the hands, given SAM vs. the placebo. Unlike non-steroidal anti-inflammatory drugs SAM is not
harmful to the intestinal tract, kidney or liver. In fact, it is used to support liver detoxification functions in anti-aging
and
certain
diseases.16-24
In the above studies, the typical dosage of SAM was 400 mg, three times per day.
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Meschino Health Comprehensive Guide to Accessory Nutrients and Essential Oils
Accessory Nutrients and Essential Oils