During the 1990s several studies have shown that Magnesium supplementation in postmenopausal women can
help to increase bone density, whether administered alone or in combination with calcium or hormone replacement
therapy. Supplementation of Magnesium in these studies ranged from 500 mg to 750 mg.21,22,23 Thus, Magnesium
is emerging as a mineral that may be important in the prevention of osteoporosis, as a synergistic nutrient with
calcium and Vitamin D.21
As well, the lower circulating levels of 1,25 dihydroxyvitamin D in aging may be a result of poor Magnesium status.
The enzyme that converts 25 hydroxyvitamin D to the 5-times more potent 1,25 dihydroxyvitamin D, is dependent
upon Magnesium as a cofactor to drive this biochemical pathway.24
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Meschino Health Comprehensive Guide to Minerals
8. Pregnancy and Preeclampsia (elevated blood pressure, fluid retention, protein loss in urine)
During pregnancy, Magnesium needs increase from 300 mg to 450 mg per day. Magnesium deficiency during
pregnancy is linked to the development of preeclampsia. The appropriate supplementation of Magnesium during
pregnancy decreases the incidence of these complications. Several double-blind studies confirm this finding.25-29