In asthmatics and individuals sensitive to sulfites supplementing with 100-200 mcg of molybdenum may reduce
sensitivity to some degree.5 Molybdenum deficiency may cause sulfite sensitivities.2
2. Wilson’s Disease
In Wilson’s disease, molybdenum and zinc supplementation can help the body excrete excess copper stores and
slow the progression of the disease. This requires higher doses of molybdenum and should only be implemented
by the at ending physician or specialists.5
Dosage Ranges
100-500 mcg of molybdenum can be used for general nutritional support or to enhance sulfite oxidase enzyme
function.6
Side Effects and Toxicity
Molybdenum is considered safe through a wide range of intakes (up to 15 mg per day), but it can interfere with the
absorption of copper.
At 10-15 mg per day it may accelerate the activity of xanthine oxidase, increasing production of uric acid and produce
gout-like symptoms. At 75-200 mcg per day, this is very unlikely.2,7
At 10-15 mg per day subjects may also experience anemia, diarrhea, weight loss, and swollen joints.8
Drug-Nutrient Interactions
Sulfate - sulfate and molybdenum compete with each other for absorption thus, high intake of one can reduce the
absorption of the other.9,10
Nutrient-Nutrient Interactions
Copper: high molybdenum intake may increase copper elimination from the body.11
www.meschinohealth.com
39
Meschino Health Comprehensive Guide to Minerals
Pregnancy and Lactation
During pregnancy and lactation, the only supplements that are considered safe include standard prenatal
vitamin and mineral supplements. All other supplements or dose alterations may pose a threat to the
developing fetus and there is generally insuf icient evidence at this time to determine an absolute level of
safety for most dietary supplements other than a prenatal supplement. Any supplementation practices
beyond a prenatal supplement should involve the cooperation of the at ending physician (e.g., magnesium
and the treatment of preeclampsia.)
References: Pregnancy and Lactation
1. Encyclopedia of Nutritional Supplements. Murray M. Prima Publishing 1998.
2. Reavley NM. The New Encyclopedia of Vitamins, Minerals, Supplements, and Herbs. Evans and
Company Inc. 1998.
3. The Healing Power of Herbs (2nd edition). Murray M. Prima Publishing 1995.
4. Boon H and Smith M. Health Care Professional Training Program in Complementary Medicine.
Institute of Applied Complementary Medicine Inc. 1997.
1. Standard Textbooks of Nutritional Science:
-
Shils M, Shike M, Olson J, Ross C. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Lippincott Williams &
Wilkins; 1993.
-
Escott-Stump S, Mahan LK, editors. Food, Nutrition and Diet Therapy. 10th ed. Philadelphia, PA: W.B. Saunders
Company; 2000.
-
Bowman B, Russell RM, editors. Present Knowledge in Nutrition, 8th ed. Washington, DC:.ILSI Press; 2001.
-
Kreutler PA, Czajka-Narins DM, editors. Nutrition in Perspective. 2nd ed. Upper Saddle River, NJ: Prentice Hall Inc.; 1987.
2. Sardesa VM. Molybdenum: an essential trace element. Nutr Clin Pract 1993;8:277-81.
3. Simons RA. Sulfite Sensitivity. Annals Allergy 1986;56:281-8.
4. Birkmayer J. Biological and clinical relevance of trace elements. Arztl lab 1990;36:284-7.
5. Murray M. Encyclopedia of Nutritional Supplements. Rocklin, CA: Prima Publishing; 1996.
Comment [c32]: Pagination?
6. Reavley N. The New Encyclopedia of Vitamins, Minerals, Supplements and Herbs. New York, NY: M. Evans and Company Inc.;