Many people suffering from Chronic Fatigue Syndrome look surprisingly well externally. An examination is necessary but it is least likely to reveal conclusive evidence. The lymph glands in the neck, under the arms or in the groin may be tender and swollen; the throat may be inflamed; or muscles may be more or less painful. Many diseases that display similar symptoms to those of CFS have to be ruled out: these include infections such as Brucellosis, Toxoplasmosis, Tuberculosis, AIDS and Epstein-Barr virus (which is responsible for glandular fever); Multiple Sclerosis, Epilepsy, Auto-Immune Disorders, Anaemia, certain forms of Cancer, Drug Addiction, Alcoholism, Depression, Anxiety; Endocrine abnormalities such as Thyroid gland related disorders; Addison’s Disease, Cushing’s Syndrome and Liver Disorders.