materials of experiments, the probe into Tian Xian Liquid and the effectiveness of its
clinical treatments. Because the results had been diligently recorded into the research
thesis, it is still difficult to transcribe them into simple, lay language. It does not matter
even if readers skip this part as long as the reader realize that any result of the clinical
experiments can show excellent anti-cancer efficacy.
From 1984 to 1996, the experiments were carried through in more than thirty
cancer research institutions and special organizations such as the American State Cancer
Center, the Chinese Medicine Research Institute of China, the Tianjin Medicine Science
Research Institute and so one. The tests were about toxicology and pharmacology. All
studied the stabilized and excellent anti-cancer properties of Tian Xian Liquid. Even if
the patients take the Liquid continuously, no harm will come to the vital internal organs
and structures such as the red blood cells, white blood cells, blood platelet, heart, liver, kidney, etc.
compounding period of the cancer cells. It is certain that its restraining rate can reach
40% to 89.1%. As for the clinical experiments done on patients, those who have not
undergone surgery, radiation or chemical treatments, who are suffering from telophase
esophagus cancer and stomach cancer, and those who experienced recurrence after
treatment, it is found that the liquid can stop the growth of the cancer cells. The actual
data include 2.6% completely healed (tumors disappeared completely), 9.3% partial relief
(tumors decreased more than half the previous size), and 77.2% stability (tumors decrease
less than half the previous size but cancer cells have stopped increasing).
What’s more, Tian Xian Liquid has the excellent effect in improving the patients’
condition and greatly solved the anorexia problem of those suffering from esophagus
cancer as well as those in pain. To the esophagus cancer patients, Tian Xian Liquid,
radiation treatment (725 cases) and chemical treatment (131 cases) were used together in
the clinical experiments. Double effects were observed; complete relief for those who
underwent radiation treatment increased by 28.3% (P<0.1) and that of the chemical
treatment increased by 25% (P<0.05). It is, therefore, certain that Tian Xian Liquid can
improve the effectiveness of radiation and chemical treatment.
Table 6: The Main Anti-Cancer Effectiveness And Functions Of Tian Xian Liquid
(1) The barrier function to cancer cells
The ingredients of Tian Xian Liquid erect barriers to the cancer cells and make them unable to continue multiplication at the growing phase of cancer cells 1.
a) It can stop cancer cells from multiplying and make them die at some point in the multiplication period.
b) It can impede and stop the breathing of cancer cells so that they die at the energy metabolism stage.
c) It can destroy cancer cells and dissolve the tumor.
(2) The function of adjusting metabolism
The Liquid restrains the multiplication of cancer cells by changing the various kinds of metabolism which are necessary for the process. In the meantime, it can improve the metabolism of the organisms affected by the cancer cells. The crude drugs that have the function of adjusting metabolism are black nightshade, climbing nightshade, angelica, and the root of red-rooted salvia.
(3) The function of great immunity improved
The Liquid can adjust internal conditions so as to strengthen the immune system while the multiplication of cancer cells is restrained. The crude drugs that support this function are ginseng, pachman, Chinese honey locust, the root of Chinese trichosanthes, etc.
(4) The functions of trace elements
The movements of trace elements can change the organism’s physiology and drive the genetic cells to destroy the cancer cells.
a) Se: the genetic cells of organic Se have the restraining function, control cancer cells and then prevent the division of mid-period cancer cells.
b) Ge: Ge can accelerate the secretions of the soluble substance II of lymph and interferon I, stimulate the autoecious anti-cancer function and control the growth and pervasion of tumors.
In addition, in the study of immunity pathology, whenever esophagus cancer
inside and outside the lymph and phagocytes become strong after the tumor samples cut
in the operation are studied through pathologic histology and electron microscope while
the cancer karyons and its cells begin to degenerate and necrosis appears.
According to the above results, it can be said that Tian Xian Liquid is the kind of
medicine with extensive usages especially the separated treatment of telophase cancers.
It can be used with chemical treatment and radiation treatment and can be considered as
the ideal Chinese medicine to prevent cancer recurrence and metastasis.
(I) The Experiments On Animal Toxicology
When the little white mouse takes Tian Xian Liquid, the absolute lethal
dose is 18.2g/kg; the smallest lethal dose is 9.1g/kg and there is no obvious sign
of toxicity. In addition, LD50 (short for lethal dose, meaning a half of lethal
dose) is 13.62±1.6g/kg (Table 7). The reason is the breathing difficulties.
Big White Mouse
Experiment (I) Of Big White Mouse
First, the big white mice are respectively fed up to 3.5g/kg, 2.8g/kg,
22.6g/kg, 18.4g/kg, 15.3g/kg of Tian Xian Liquid. After a week’s observation,
the obvious toxic reaction is not found.
Experiment (II) Of Big White Mouse
Each mouse is fed 4.21g/kg every day. The total time is ninety days. The
weights of the big mice of the medicine-using group grow more and more slowly
than those of the non-medicine-using group. There is no obvious influence to the
functions of the red blood cells, white blood cells, blood platelet, heart, kidney,
liver, etc. With the biological dissections and contraction of the mice of forty-five
days and those of ninety days, there is no apparent damage.
Cat
The cats respectively take 0.7g/kg, 0.6g/kg of Tian Xian Liquid. More
than half of the two groups of cats vomit several hours after taking the medicine.
At the same time, there are changes on the electrocardiograms and the movements
of their hearts become slow. The hearts of 1/3 of the excessive medicine-using
group are damaged by the conduction Block III. The symptoms of ventricular
reaction appear, such as induced by digitalis (used as cardiac stimulant, the
medicinal plant origination from Europe). Then the cats die. The surviving cats
stabilize in seven hours after they are fed Tian Xian Liquid. Based on the
foregoing acute toxic reaction, Tian Xian Liquid belongs to the medicine without
toxicity. The hypersensitivities to toxic reactions of various kinds of animals are
different. In addition, patients who take digitalis take this medicine.
Table 7: Parameter of the Acute Toxic Experiments of Tian Xian Liquid
The absolute lethal dose 18.2(g/kg)
The minimal lethal dose 9.1(g/kg)
The shortest time to die after taking 4 hours
The longest time to die after taking 3 days
The average surviving time for dying animals 15 days
The time for toxic animals to stabilize 15 days
LD50 13.62±1.6(g/kg)
(Notes: The experiment group of Kunming mice arranges 7 phases of dispensing dose
and investigate the conditions of 10 mice. The maximum dose is the maximum dose.
The dose reduces by 0P x 1 at 1:07. The group observes the weight for 6 days after the
medicine has been taken for 3 days, then calculate LD50 with Probity until (average 5,
having the normal variable with standard warp 1).
(II) The Function Of Cell Toxicity
Tian Xian Liquid is made from crude drugs with strong toxicity (the root
of Chinese trichosanthes, indigo, hedyotis, black nightshade, etc.). The
experiments of the American State Cancer Center prove that Tian Xian Liquid has
the cell toxicity against ten kinds of cancers (lung cancer, breast cancer, leukemia,
Zhivay mother cell tumor, kidney cancer, malignant melanoma, brain cancer,
stomach cancer) and forty-eight kinds of cancer cell strains. It can stop not only
the protein compounding, which is necessary for the growth of cancer cells, but
also impede the multiplication period of cancer cells. Further, it accelerates the dissolution of cancer cells. The lethal characteristic of Tian Xian Liquid is related
to the density and the term of validity.
(III) The Influence To The Cell Period And DNA Compounding
The characteristic of Tian Xian Liquid’s effectiveness against cancer
tumors is that it can directly upset the DNA compounding of cancer tumor cells.
On the basis of density differences, Tian Xian Liquid can restrain the DNA
compounding of HeLa cells (a kind of cancer cell found in a Tzukung cancer
patient by Dr. George Gal of John Hopkins Hospital in 1951) and change the
multiplication period of the said cancer cells. Table 8 shows the liquid with the
density of 10~20mg/ml can prevent the divisions of cells in the period G2 and M
and most of HeLa cells appear in the period of G2 and M. If the density increases
to 40mg/ml, it obviously restrains the DNA compounding of cancer cells and
even the DNA of the cancer cells decrease. The cells of the period G1 and M are
hypersensitive to radiations. Tian Xian Liquid had the obvious effects of
restraining the lethal ability of cancer cells in the period G2 and M when used
with radiation treatments. Tian Xian Liquid shows the obvious restraining
function to DNA/TOP of the human body. The forming of the marker with these
ferments restrain the compounding of protein. In other words, it destroys DNA.
Table 8: The Influence of Tian Xian Liquid to HeLa cells and DNA contents
Object Group 25 60 15
Tian Xian Liquid 6 50 44 10 μ g/ml
20 μ g/ml 1 19 80
30 μ g/ml 17 60 23
40 μ g/ml 78 20 2
(IV) The Strengthening Effectiveness To Radiation Therapy
We use the anoxia HeLa cells and the forming manner of the growing
colony (a kind of segregated thallus or the multiplied cell colony in the growth
media) to study the effectiveness to radiation therapy. The counting of Seven
Coulombs (to take the charge S1 as a unit, the charges transferred in one minute
by current A1 added the fixed number equals the charges of 18 times of 6.25*10)
and computer simulations are the typical ways of attacking markers once. The
life curve of cells treated with A, B equation indicates that Tian Xian Liquid has
the strengthening effectiveness. However, when Tian Xian Liquid improves the
efficacy of radiation treatment, it is based on the radiation amount.
(V) The Restraining Function To The Tested Tumors
The experiment is carried out in which mice and weasels are transplanted
with the adrenalin entity of tumor S180, adrenalin ascites carcinoma, ruminant
stomach (the first stomach of ruminant), flat tumor, lung cancer Levis, mouse
leukemia L1210. Thirty days later, the cancer tumor planted group is divided into
two, one is Tian Xian Liquid group and the other is the non-Tian Xian Liquid
group. The average diameter of the cancer tumors in the non-Tian Xian Liquid
group is 8.1mm while the average diameter of cancer tumor in Tian Xian Liquid
group is 8.6mm. The dose of Tian Xian Liquid group is 2-5g/kg once every day
and the total time is twenty-one days. Twenty-four hours after the last dose, the
animals in each group begin to die and the tumors are then weighed. The results
show that the restraining rates of Tian Xian Liquid to solid tumor and flat
proventiculus tumor are 58.7 (P<0.01) to 2g/kg and 89.1% (P<0.001) to 5g/kg
(Table 9).
(VI) The Data On The Clinical Cases In The Cancer Treatment
In the clinical experiments, the patients of the telophase peptic cancer are
continuously given the medicine. 10 ml of the medicine is given three times a
day.
Table 9: The Effectiveness of Tian Xian Liquid to Cancer
10 2 21 35.6% S180 10 5 21 48.3%
10 Comparing groups 21 - 9 2 18 54.9% Adrenalin 9 5 18 57.6% Entity 9 Comparing groups 18 - 5 2 20 46.9% Lung cancer 5 5 20 56.4%
Lewis 5 Comparing groups 20 - Flat 6 2 21 58.7% Proventriculus 6 5 21 89.1% Tumor 6 Comparing groups 21 - Adrenalin 10 2 18 8.0 days Ascites 10 5 18 7.5 days Carcinoma 10 Comparing groups 18 - 6 2 14 8.2 days L1210 6 5 14 8.4 days 6 Comparing groups 14 -
More than thirty medical organizations in Beijing, Tianjin and Shanghai
conducted the clinical experiments of Tian Xian Liquid to 696 cases of telophase esophagus cancer, stomach cancer, and intestinal cancer. The evaluation assured
that the successful cases are 620 except the cases where cancer stabilized
according to the present standard of China. It is also certain that Tian Xian Liquid
enjoys high success rate (Table 10).
Table 10: The Effectiveness of Single Use of Tian Xian Liquid
Names
Of tumors Esophagus cancer Stomach cancer Intestines cancer Lung cancer
Liver cancer
Adenoma of breast Brain tumor
Number of Successful Failed Effectiveness cases Cases Cases Rate 225 201 24 89.3 376 334 42 88.8 95 85 10 89.5 94 73 21 77.7 34 25 9 73.5 78 56 22 71.8 46 28 18 61.0
(VIII) The Clinical Treatment Of Esophagus Cancer With Simultaneous Use OfIf the patient of esophagus cancer takes Tian Xian Liquid before
operation, it is found that a great number of lymph cells penetrate into the
cancer tissues or the surrounding areas of the cancer cells and the cancer cells
begin to become necrotic as observed from the sample removed in the
operation. At the same time, the karyons of cncer cells and the material cells
start to degenerate. From these results, it is sure that Tian Xian can improve the immune system. What’s more, in some surgery cases, the tissues around the
tumor become malacic and easy to fall off which can make the operation
proceed smoothly. Because Tian Xian Liquid can greatly improve the immune
system, the recurrence rate after surgery has decreased by 44% from 69% to
25% for removal operation and the cases of the residual and transfer tumor
tissues.
(IX) The Clinical Treatment With The Simultaneous Use Of Tian Xian Liquid
The clinical treatments of the patients of esophagus cancers of middle
phase and telophase with radiation therapies of different radioactive rays and
Tian Xian Liquid have been successfully implemented. It can be deduced from
results that the efficacy of both treatments have been greatly improved with the
simultaneous applications. That is to say, Tian Xian Liquid indeed has
excellent restraining function on esophagus cancer (Tables 11 and 14).
Table 11: The success rate of “900ml of Tian Xian Liquid + half of DT4000cgy
Therapy Total Success rate (%)
Tian Xian Liquid and Radiation 80
Single radiation 45
Table 12: The success rate of “1350ml of Tian Xian Liquid + half of DT4000cgy irradiation” and “single radiation with half of DT6000~7500cgy irradiation” Therapy Total Success rate (%) Tian Xian Liquid and Radiation 80
Single Radiation 60
Table 13: The success rate of “1350ml of Tian Xian Liquid + half of DT6000~7500cgy irradiation” and “single radiation with total DT6000~7500cgy irradiation”
Therapy Total Success rate (%) Tian Xian Liquid and Radiation 95
Single Radiation 60
Table 14: The success rate of “1350ml of Tian Xian Liquid + total DT6000~7500cgy irradiation” and “single radiation with total DT4000cgy irradiation” to the esophagus cancers of middle and telophase.
Therapy Total Success Rate (%) Tian Xian Liquid and Radiation 71.4
Single Radiation 11.9
Table 15: The contrast of the successes of Tian Xian Liquid + chemical anti-cancer medication as against single anti-cancer medicine to esophagus cancer Therapy Total Success Rate (%) Tian Xian Liquid + chemical anti-cancer
medication 79.2
Single anti-cancer medicine 11.9
Sickness
Symptoms And Hair Vomiting Loss
Catarrh Reduction of White blood
cells
Reduction of Reduction blood of
(%) 82.3 79.3 83.6 93.7 98.1 88.5
(X) The Clinical Treatment With The Simultaneous Uses Of Tian Xian Liquid
The experiment group and comparative group are arranged. Tian Xian
Liquid and anti-cancer medication are used simultaneously on the patients of
esophagus cancer in the middle phase and telophase. The result shows that Tian
Xian Liquid can in a short period manifest effectiveness against cancer and can
minimize the side effects of the arrest of bone marrow caused by the anti-cancer
drugs (Tables 15 and 16). In addition, the most attractive aspect is that lund
cancer and lymphoma are eased in a short span after taking the Liquid with the
anti-cancer medicine. The long-term effect is still being studied in further clinical
tests. This item of the experiment indicates that the simultaneous usage of Tian
Xian Liquid and chemical anti-cancer drugs can improve the cure rate of
esophagus cancer to 25%.
(XI) The Side Effects Of Tian Xian Liquid
20 ml of Tian Xian Liquid is used once for clinical experiments. Though
3% of the patients feel uncomfortable in their stomachs and have a jaded appetite,
the majority came around after taking the Liquid continuously. Added to this,
among the patients who take only Tian Xian Liquid, no harm to their internal
organs such as