Biology of Aging by National Institute of Aging - HTML preview

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ALTERING OLDER

ADULTS' IMMUNITY

Our ability to survive the germs

in older people, or is immunosenescence

around us is based on a tightly

somehow beneficial within the context of

controlled immune system. Too

the aging body?

little of an immune response

Given the delicate balance of the

makes us susceptible to infection,

immune system, gerontologists suspect that,

including life-threatening pneumonia.

along with its more obvious negative con-

Conversely, an overactive immune response

sequences, immunosenescence might have

is at the root of autoimmune diseases

a protective role in seniors. More research

common among older people and may

is needed before scientists fully understand

contribute to age-related chronic diseases

the aging immune system and determine

like Alzheimer’s disease, osteoarthritis,

whether changing an immune response

diabetes, and heart disease. So, should sci-

would lead to an increase or a decrease in

entists try to change the immune response

health span and lifespan in humans.

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