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How does genetic testing in a research setting differ from clinical genetic testing?
The main differences between clinical genetic testing and research testing are the purpose of the test and who receives the results. The goals of research testing include finding unknown genes, learning how genes work, and advancing our understanding of genetic conditions. The results of testing done as part of a research study are usually not available to patients or their healthcare providers. Clinical testing, on the other hand, is done to find out about an inherited disorder in an individual patient or family. People receive the results of a clinical test and can use them to help them make decisions about medical care or reproductive issues.
It is important for people considering genetic testing to know whether the test is available on a clinical or research basis. Clinical and research testing both involve a process of informed consent in which patients learn about the testing procedure, the risks and benefits of the test, and the potential consequences of testing.
For more information about the differences between clinical and research testing:
GeneTests outlines the major differences between clinical tests and research tests (http://www.ncbi.nlm.nih.gov/projects/GeneTests/static/concepts/primer/ primerwhatistest.shtml). Scroll down to the sections "What is a Clinical Test?" and "What is a Research Test?”