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sensitivity obtained from the system with the unbalanced configuration was increased by 4

2.3 Results and Discussion of Complex OCT system

The performance of the complex conjugate ambiguity resolution in our 3x3 Mach-Zehnder

dB compared to the system with the balanced configuration. This is due to better utilization

SS-OCT system with the unbalanced configuration could be quantified by comparing the

of optical power with our unbalanced differential detection technique.

complex conjugate resolved A-scans with the unresolved A-scans. Measurements were

taken using a -55dB reflector including coupling loss in the sample arm as shown in Fig. 4.

The reference mirror was adjusted to a position such that the difference in optical path

length between the two interferometer arms was 500 m. The extra background noise was

subtracted by measuring the reference arm signals with the sample arm blocked.

0.1

-30

-30

-40

-40

-50

-50

0

-60

er (dB)

-60

er (dB)

27dB

-70

(b)

-70

(a)

-80

Pow

-80

Pow

Fig. 6. In vivo images of human finger tip acquired by our full range swept-source optical

Intensity (a.u.)

90o

-90

-90

-0.1

0 1 2 3 4 5 6 7 8

coherence tomography using the 3x3 Mach-Zehnder interferometer with unbalanced

0 1 2

1000

1100

3 4 5 6 7 8

Ph ase Pixel

differential detection technique. (a): the image was generated using only a single detector.

Depth (mm)

Depth (mm)

(b): the complex signals were used.

(a)

(b)

(c)

Fig. 5. The experimental results of the complex conjugate artifact resolution with our 3x3

Fig. 6 shows in vivo images of a human finger tip acquired by our full range swept-source

MZI SS-OCT in the unbalanced differential detection with 3x3 coupler ratio of

optical coherence tomography using the 3x3 Mach-Zehnder interferometer with unbalanced

0.39/0.29/0.32 in 500 m path length difference of the sample and reference arms. (a):

differential detection technique. The resolutions of the axial and lateral are 10 m and 27 m,

Measured interferometric signals of the output P

respectively. The pixel size of the images is 800x900 in correspond to the image size of

1 and P2 on two detectors with phase shift

of 90

3x4mm. In Fig. 6 (a), the image was generated using only a single detector, and

o. Inset: Measured full interferometric signals of the output P1 and P2. (b): A-scan signals

obtained by IFT from a single detector include the complex conjugate artifacts. (c): A-scan

demonstrates the folded artifact images. In Fig. 6 (b), the complex signal was used

signals obtained by IFT directly from the output signals at the two detectors with

demonstrating artifact-free imaging over a depth range of 3 mm.

suppressions of the complex conjugate peaks of 27 dB.

3. High Performance Wavelength-Swept Laser for Optical Coherence

Fig. 5 (a) shows measured waveforms of the output signal P1 and P2 from our unbalanced

Tomography

SS-OCT system with 3x3 port configuration as coupler ratio of 0.39/0.29/0.32, i.e., we

connected the lowest power port of the 3x3 coupler to the 2x2 coupler. The input power

3.1 Optical Filter Design for Swept Laser

ratios in this unbalanced setup were 2.8 and 2.4 for the two detectors, respectively. We

Fig. 7 shows a schematic diagram of the FDML wavelength swept laser with a long fiber

noticed from the full interferometric signals of the output P1 and P2 shown in the inset of the

ring cavity. A SOA is used as the gain medium in the ring cavity which has a central

Fig. 5 (a) that the DC values of the waveforms in the unbalanced system were removed by

wavelength of 1300 nm. The SOA is considered the most suitable gain medium for OCT

the high-pass filter of the detectors. Because a phase difference of 90o between the

applications: high small-signal gain, broadband gain spectra, and high relaxation resonance

interferometric signals P1 and P2 was obtained, the data of measured P1 and P2 was frequencies. The wavelength selection was achieved by a polygon-based high-speed

automatically become quadrature signals. Therefore, a minimized complex conjugate

narrowband optical scanning filter. The unidirectional wavelength sweep of a polygon

38

Biomedical Imaging

scanner, as opposed to the inherently bidirectional Fabry-Perot filter, is better matched to

and 40 mm, a polygon scanner with 72 facets and a facet area of 6.35x2.77 mm2 (Mao et al.,

the gain properties of an SOA. A mode-locked laser resonator was implemented using a

2009). A summary of the input parameters and simulation results are listed in Table 1. The

long single mode fiber (SMF). The polygon-based reflection-type scanning narrow-bandpass

observed 0.5 mm chromatic focal shift after F1 on both end of the spectrum wavelength ends

filter (Yun et al., 2003) includes an optical fiber collimator, an optical diffraction grating, an

were compensated for our double-pass arrangement. A change of the focal spot at the image

afocal telescope, a polygon scanner, and a planar mirror. A collimated Gaussian beam with

plane from circular to elliptical at the edge wavelengths, shown in Fig. 8, resulted in a nearly

a broad optical spectrum from the SOA was first spread by the optical grating and then

Gaussian output spectrum due to lower coupling efficiencies at those edges.

converged to the polygon by the telescope. The telescope, made of two achromatic doublets,

controls both the beam size and angles. A planar mirror was placed after the polygon to

reflect only the spectral component with normal incidence to the fiber. We note that the

Input Parameter

Value

Simulation Result

Value

sweeping angle of the intermediate reflection from the polygon facet doubles the polygon’s

Center

1305 nm

Collimate beam width (1/e2)

1.89 mm

effective rotation angle, so that the free spectral range (FSR) of this filter is twice than when

wavelength

the polygon simply retro-reflects the light back to the telescope. The orientation of the

Input fiber,

Single mode

Spectral sweeping range

± 55 nm

grating incidence angle and the rotation direction of the polygon facet determine the

core & NA

9 m & 0.11

direction of the wavelength tuning. The arrangement in Fig. 7 produced a unidirectional

Collimate lens

f = 10 mm

FWHM bandwidth at central

0.16 nm

increase of the wavelength that resulted in higher optical power output. An optical fiber

 = 6mm

circulator was used to couple the light between the ring cavity and the filter. Three fiber

Grating density

830g/mm

Diverging angle after grating

-2.637o

polarization controllers were placed before the SOA, the circulator and the grating to

incidence angle

69 deg

at 1250 and 1360nm to central

+2.656o

optimize their polarization, respectively (Mao et al., 2009). The CW wavelength-swept light

Doublet 1

F1 = 75 mm

Converging angle at polygon

+4.944 o

was coupled out of the cavity by a fiber coupler positioned after the SOA.

= 25.4mm

at 1250 and 1360nm to central

-4.979o

Doublet 2

F2 = 40 mm

1/e2 Beam width at Polygon

2.78 mm

Laser Output

= 25.4mm

Polygon

facet

72

Chromatic focal shift after F1

0.50 mm

Polygon

Coupler

PC

number

at 1250 and 1360nm to central

0.51 mm

Doublet2

Polygon angle

Image chromatic focal shift at

< 0.1 mm

per facet

1250 and 1360nm to central

< 0.1 mm

Mirror

Polygon radius

31.75 mm

Image spot size at 1250,

120 x 10 m2

Circulator

SOA

1305, and 1360nm

2.6 x 2.6 m2

110 x 9 m2

Doublet1

Fiber Spool

Polygon

facet

6.35x2.77mm2

Coupling efficiency at 1250,

7%

PC

Grating

area

1305, and 1360nm

38%

8%

Table 1. The parameters of the polygon scanning filter obtained from ZEMAX simulation.

Fig. 7. Schematic diagram of a FDML wavelength-swept laser shown with a ZEMAX ray-

tracing of the polygon-based narrow-band filter.

1250nm

1305nm

1360nm

The parameters of the polygon scanning filter and its components were investigated by

using a commercial optical modeling software ZEMAX (ZEMAX Development Corp., WA,

 m

m

 m

USA). The ray-tracing layout of the optical filter is shown in Fig. 7 where a non-sequential

150

10

120

ZEMAX component was used to model the polygon scanner. As the polygon was rotated

clockwise by one facet, one full cycle of the continuous spectrum was swept. To achieve an

optical filter with a FWHM linewidth of 0.16 nm, central wavelength of 1305 nm, free

Fig. 8. Imaging spot size at 1250 nm (left), 1305 nm (central), and 1360 nm (right) of the filter

spectral range (FSR) of 110 nm, 100% duty cycle, minimum beam clipping and maximum

from ZEMAX simulation.

coupling efficiency, the following optical components were chosen: a fiber collimator with

10 mm focal length and 1/e2 beam width of 1.89 mm, a grating with a groove frequency of

The diffraction grating equation is given by (Hecht, 1979), λ = (sin  + sin β)/ T, where λ is

830/mm and an incident angle of 69o, two achromatic doublets with focal lengths of 75 mm

the wavelength, T is the groove frequency, and  and β are the incident and the diffracted

index-47_1.png

Full Range Swept-Source Optical Coherence

Tomography with Ultra Small Fiber Probes for Biomedical Imaging

39

scanner, as opposed to the inherently bidirectional Fabry-Perot filter, is better matched to

and 40 mm, a polygon scanner with 72 facets and a facet area of 6.35x2.77 mm2 (Mao et al.,

the gain properties of an SOA. A mode-locked laser resonator was implemented using a

2009). A summary of the input parameters and simulation results are listed in Table 1. The

long single mode fiber (SMF). The polygon-based reflection-type scanning narrow-bandpass

observed 0.5 mm chromatic focal shift after F1 on both end of the spectrum wavelength ends

filter (Yun et al., 2003) includes an optical fiber collimator, an optical diffraction grating, an

were compensated for our double-pass arrangement. A change of the focal spot at the image

afocal telescope, a polygon scanner, and a planar mirror. A collimated Gaussian beam with

plane from circular to elliptical at the edge wavelengths, shown in Fig. 8, resulted in a nearly

a broad optical spectrum from the SOA was first spread by the optical grating and then

Gaussian output spectrum due to lower coupling efficiencies at those edges.

converged to the polygon by the telescope. The telescope, made of two achromatic doublets,

controls both the beam size and angles. A planar mirror was placed after the polygon to

reflect only the spectral component with normal incidence to the fiber. We note that the

Input Parameter

Value

Simulation Result

Value

sweeping angle of the intermediate reflection from the polygon facet doubles the polygon’s

Center

1305 nm

Collimate beam width (1/e2)

1.89 mm

effective rotation angle, so that the free spectral range (FSR) of this filter is twice than when

wavelength

the polygon simply retro-reflects the light back to the telescope. The orientation of the

Input fiber,

Single mode

Spectral sweeping range

± 55 nm

grating incidence angle and the rotation direction of the polygon facet determine the

core & NA

9 m & 0.11

direction of the wavelength tuning. The arrangement in Fig. 7 produced a unidirectional

Collimate lens

f = 10 mm

FWHM bandwidth at central

0.16 nm

increase of the wavelength that resulted in higher optical power output. An optical fiber

 = 6mm

circulator was used to couple the light between the ring cavity and the filter. Three fiber

Grating density

830g/mm

Diverging angle after grating

-2.637o

polarization controllers were placed before the SOA, the circulator and the grating to

incidence angle

69 deg

at 1250 and 1360nm to central

+2.656o

optimize their polarization, respectively (Mao et al., 2009). The CW wavelength-swept light

Doublet 1

F1 = 75 mm

Converging angle at polygon

+4.944 o

was coupled out of the cavity by a fiber coupler positioned after the SOA.

= 25.4mm

at 1250 and 1360nm to central

-4.979o

Doublet 2

F2 = 40 mm

1/e2 Beam width at Polygon

2.78 mm

Laser Output

= 25.4mm

Polygon

facet

72

Chromatic focal shift after F1

0.50 mm

Polygon

Coupler

PC

number

at 1250 and 1360nm to central

0.51 mm

Doublet2

Polygon angle

Image chromatic focal shift at

< 0.1 mm

per facet

1250 and 1360nm to central

< 0.1 mm

Mirror

Polygon radius

31.75 mm

Image spot size at 1250,

120 x 10 m2

Circulator

SOA

1305, and 1360nm

2.6 x 2.6 m2

110 x 9 m2

Doublet1

Fiber Spool

Polygon

facet

6.35x2.77mm2

Coupling efficiency at 1250,

7%

PC

Grating

area

1305, and 1360nm

38%

8%

Table 1. The parameters of the polygon scanning filter obtained from ZEMAX simulation.

Fig. 7. Schematic diagram of a FDML wavelength-swept laser shown with a ZEMAX ray-

tracing of the polygon-based narrow-band filter.

1250nm

1305nm

1360nm

The parameters of the polygon scanning filter and its components were investigated by

using a commercial optical modeling software ZEMAX (ZEMAX Development Corp., WA,

 m

m

 m

USA). The ray-tracing layout of the optical filter is shown in Fig. 7 where a non-sequential

150

10

120

ZEMAX component was used to model the polygon scanner. As the polygon was rotated

clockwise by one facet, one full cycle of the continuous spectrum was swept. To achieve an

optical filter with a FWHM linewidth of 0.16 nm, central wavelength of 1305 nm, free

Fig. 8. Imaging spot size at 1250 nm (left), 1305 nm (central), and 1360 nm (right) of the filter

spectral range (FSR) of 110 nm, 100% duty cycle, minimum beam clipping and maximum

from ZEMAX simulation.

coupling efficiency, the following optical components were chosen: a fiber collimator with

10 mm focal length and 1/e2 beam width of 1.89 mm, a grating with a groove frequency of

The diffraction grating equation is given by (Hecht, 1979), λ = (sin  + sin β)/ T, where λ is

830/mm and an incident angle of 69o, two achromatic doublets with focal lengths of 75 mm

the wavelength, T is the groove frequency, and  and β are the incident and the diffracted

40

Biomedical Imaging

angles of the beam, respectively, with respect to the normal axis of the grating. The

simulated spectrum is the product of the filter spectrum (due to different filter coupling

sweeping wavelength ( ) could be expressed as (Yun et al., 2003):

efficiencies at different wavelengths) and the spontaneous emission spectrum of the used

(9)

SOA. A full sweeping wavelength range of 113 nm and FWHM bandwidth of 90 nm at

d  1

( / T)cos0( F 2 / F 1) 

d

central wavelength of 1303 nm measured from our swept laser were obtained. We note that

where d is the sweeping angle of the polygon scanner and  0 is the angle between the

the shape of the measured spectrum is close to a Gaussian distribution. This bandwidth of

optical axis of the telescope and the grating’s normal. Since d =2Rdt for a polygon scanner,

the swept laser would correspond to 8.3 m axial resolution in the air in OCT. The measured

we could get a linear relationship between the sweeping wavelength and the sweeping time

sweeping FWHM bandwidth of the FDML swept laser was 1.43 times higher than the

by integrating Eq. (9):

simulated spectrum. This increase in bandwidth is due to higher optical gains in the smaller

4 cos 

signal range at the edge wavelengths than the central wavelength. While keeping the

0 F 2 R

 ( t )

  

1

t

(10)

polygon static, two spectra were measured using the highest resolution of the OSA (0.01

TF 1

nm) at the center wavelength of 1303 nm and at the dual-edge wavelengths of 1248.0 nm

Our design results in a wavelength sweeping rate of 7.31 mm/s.

and 1358.2 nm, shown in Fig. 9 (b) in addition to the dynamic spectrum for comparison. A

distance of 110.2 nm between the two simultaneous existing peaks corresponds to the FSR of

the filter, which is in good agreement with the design specifications of FSR of 110 nm. We

3.2 Swept Laser Construction

also note that the static spectra of our FDML swept laser had a FWHM linewidth of 0.015

A Fourier-domain mode-lock wavelength-swept laser based on polygon scanning filter and

nm at the central wavelength as shown in the inset of the Fig. 9 (b). The measured filter

semiconductor optical amplifier was constructed. A high efficiency InP/InGaAsP quantum

linewidth was 0.17 nm at the same wavelength as shown in the Fig. 9 (c). We found the

well SOA (BOA 1132, Covega) was used as the laser gain medium with a saturation output

measured laser linewidth was 11.3 times smaller than that of the filter. The linewidth of

power of 19 dBm, small signal gain of 30 dB and FWHM bandwidth of 93 nm. The material

filter in the edge wavelength range increased which could be caused by the off-axis effect of

structure of the quantum well active region of the SOA was optimized to increase the output

the doublet; however, this effect was diminished by the FDML method as shown in Fig. (c).

power and bandwidth. A 72-facet polygon scanner (SA34, Lincoln Laser) that optimized for

Fig. 9 (d) shows average output power of the swept laser versus the injection current