Some observational evidence and at least one intervention study suggests that a marginal deficiency of copper
causes a rise in LDL-cholesterol (approximately 33 mg/dL) and a decrease in HDL-cholesterol (approximately 18.7
mg/dL).
Epidemiological evidence suggests that a marginal or absolute copper deficiency is associated with elevated
cholesterol levels, myocardial infarction (heart at ack), arterial damage, and increased cardiovascular mortality.
Animal research also supports this relationship.4,5 In humans 2 mg per day has been shown to decrease LDL-
cholesterol oxidation.6