Any new medication or supplement that a post-kidney transplant patient requests
should be reviewed first before prescribing
St. John’s Wort, rifampin, phenytoin, and carbamazepine can all lower cyclosporine
levels
Diltiazem, verapamil, and erythromycin can increase cyclosporine levels
Cyclosporine can interfere with certain statins such as simvastatin, increasing the risk
of statin-induced rhabdomyolysis
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References:
1. Bakris GL et al. Angiotensin-Converting Enzyme Inhibitor-Associated Elevations in
Serum Creatinine: Is this a Cause for Concern? Arch Intern Med. 2000; 160 (5): 685 –
693. PMID: 10724055
2. Douglas K et al. Meta-analysis: The Effect of Statins on Albuminuria. Ann Intern Med.
2006; 145 (2): 117 – 124. PMID: 16847294
3. Levey AS et al. Definition and Classification of Chronic Kidney Disease: A Position
Statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int.
2005; 67 (6): 2089 – 2100. PMID: 15882252
4. Paige NM et al. The Top 10 Things Nephrologists Wish Every Primary Care Physician
Knew. May Clin Proc. 2009 Feb; 84 (2): 180 – 186. PMID: 19181652
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